Triamterene / HCTZ Online


Buy Dyazide (Triamterene/Hydrochlorothiazide) antihypertensive drug and diuretic
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DYAZIDE (TRIAMTERENE, HYDROCHLOROTHIAZIDE) CAPSULES: PRESCRIBING INFORMATION

DESCRIPTION

Each capsule of Dyazide (Hydrochlorothiazide and Triamterene) for oral use, with opaque red cap and opaque white body, contains hydrochlorothiazide 25 mg and triamterene 37.5 mg, and is imprinted with the product name Dyazide and SB. Hydrochlorothiazide is a diuretic/antihypertensive agent and triamterene is an antikaliuretic agent.

Hydrochlorothiazide is slightly soluble in water. It is soluble in dilute ammonia, dilute aqueous sodium hydroxide, and dimethylformamide. It is sparingly soluble in methanol.

Hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide 1,1dioxide.

At 50°C, triamterene is practically insoluble in water (less than 0.1%). It is soluble in formic acid, sparingly soluble in methoxyethanol, and very slightly soluble in alcohol.

Triamterene is 2, 4, 7-triamino-6-phenylpteridine.

Inactive ingredients consist of benzyl alcohol, cetylpyridinium chloride, FD&C Yellow No. 6, D&C Red No. 33, gelatin, lactose, glycine, magnesium stearate, microcrystalline cellulose, polysorbate 80, povidone, sodium starch glycolate, titanium dioxide, and trace amounts of other inactive ingredients.

Capsules of Dyazide meet Drug Release Test 3 as published in the current USP monograph for Triamterene and Hydrochlorothiazide Capsules.


CLINICAL PHARMACOLOGY

Dyazide clinical pharmacology


CLINICAL TRIALS

Dyazide clinical trials


INDICATIONS AND USAGE

Dyazide indications and usage


CONTRAINDICATIONS

Dyazide contraindications


WARNINGS

Dyazide warnings


PRECAUTIONS

Dyazide precautions


LABORATORY TESTS

Dyazide laboratory tests


DRUG INTERACTIONS

Dyazide drug interactions


NONCLINICAL TOXICOLOGY

Dyazide nonclinical toxicology


USE IN SPECIFIC POPULATION

Dyazide use in specific population


ADVERSE REACTIONS

Dyazide adverse reactions


DOSAGE AND ADMINISTRATION

The usual dose of Dyazide (Triamterene with HCTZ) capsules is one or two capsules given once daily, with appropriate monitoring of serum potassium and of the clinical effect.


OVERDOSAGE

Dyazide overdosage


HOW SUPPLIED

Capsules containing 25 mg hydrochlorothiazide and 37.5 mg triamterene, in bottles of 1,000 capsules; in Patient-Pak unit-of-use bottles of 100.

They are supplied as follows:

Storage

Store at controlled room temperature 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). Protect from light. Dispense in a tight, light-resistant container.

Manufactured and distributed by GlaxoSmithKline pharmaceutical company and its divisions.

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