Triamterene / HCTZ Online


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DYAZIDE (TRIAMTERENE, HYDROCHLOROTHIAZIDE) CAPSULES: OVERDOSAGE

Electrolyte imbalance is the major concern. Symptoms of overdose by Dyazide (Hydrochlorothiazide, Triamterene) reported include: nausea, polyuria, vomiting, lassitude, weakness, fever, flushed face, hyperactive deep tendon reflexes. If hypotension occurs, it may be treated with pressor agents such as levarterenol to maintain blood pressure. Carefully evaluate the electrolyte pattern and fluid balance. Induce immediate evacuation of the stomach through emesis or gastric lavage. There is no specific antidote.

Reversible acute renal failure following ingestion of 50 tablets of a product containing a combination of 50 mg triamterene and 25 mg hydrochlorothiazide has been reported.

Although triamterene is largely protein-bound (approximately 67%), there may be some benefit to dialysis in cases of overdosage.

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